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1

Protein–protein interactions in polyketide synthase–nonribosomal peptide synthetase hybrid assembly lines

Miyanaga, Akimasa, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Natural Product Reports

Année:

2018

Langue:

english

Fichier:

PDF, 5.35 MB

english, 2018

2

A Stereoselective Vanadium-Dependent Chloroperoxidase in Bacterial Antibiotic Biosynthesis

Bernhardt, Peter, Okino, Tatsufumi, Winter, Jaclyn M., Miyanaga, Akimasa, Moore, Bradley S.

Journal:

Journal of the American Chemical Society

Année:

2011

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2011

3

Evidence that far-infrared radiation promotes growth of Xenopus laevis

Robert Shiurba, Tatsuo Hirabayashi, Shin Kiyokawa, Akimasa Fukui, Yuko Miyanaga, Issey Kojima, Makoto Asashima

Journal:

Advances in Space Research

Année:

1999

Langue:

english

Fichier:

PDF, 302 KB

english, 1999

4

Mutational and structural analysis of cobalt-containing nitrile hydratase on substrate and metal binding

Akimasa Miyanaga, Shinya Fushinobu, Kiyoshi Ito, Hirofumi Shoun, Takayoshi Wakagi

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 483 KB

english, 2004

5

Characterization of a chimeric enzyme comprising feruloyl esterase and family 42 carbohydrate-binding module

Takuya Koseki, Keiji Mochizuki, Hiroe Kisara, Akimasa Miyanaga, Shinya Fushinobu, Tetsuya Murayama, Yoshihito Shiono

Journal:

Applied Microbiology and Biotechnology

Année:

2010

Langue:

english

Fichier:

PDF, 185 KB

english, 2010

6

Enzymatic synthesis of bis-5-alkylresorcinols by resorcinol-producing type III polyketide synthases

Miyanaga, Akimasa, Horinouchi, Sueharu

Journal:

The Journal of Antibiotics

Année:

2009

Langue:

english

Fichier:

PDF, 306 KB

english, 2009

7

Crystal Structure of Cobalt-Containing Nitrile Hydratase

Akimasa Miyanaga, Shinya Fushinobu, Kiyoshi Ito, Takayoshi Wakagi

Journal:

Biochemical and Biophysical Research Communications

Année:

2001

Langue:

english

Fichier:

PDF, 467 KB

english, 2001

8

Mutational analysis of N-glycosylation recognition sites on the biochemical properties of Aspergillus kawachii α-l-arabinofuranosidase 54

Takuya Koseki, Yozo Miwa, Yuichiro Mese, Akimasa Miyanaga, Shinya Fushinobu, Takayoshi Wakagi, Hirofumi Shoun, Hiroshi Matsuzawa, Katsumi Hashizume

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Année:

2006

Langue:

english

Fichier:

PDF, 418 KB

english, 2006

9

Flavin-mediated dual oxidation controls an enzymatic Favorskii-type rearrangement

Teufel, Robin, Miyanaga, Akimasa, Michaudel, Quentin, Stull, Frederick, Louie, Gordon, Noel, Joseph P., Baran, Phil S., Palfey, Bruce, Moore, Bradley S.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 658 KB

english, 2013

10

The crystal structure of the amidohydrolase VinJ shows a unique hydrophobic tunnel for its interaction with polyketide substrates

Shinohara, Yuji, Miyanaga, Akimasa, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2014

11

The crystal structure of d-mandelate dehydrogenase reveals its distinct substrate and coenzyme recognition mechanisms from those of 2-ketopantoate reductase

Miyanaga, Akimasa, Fujisawa, Shinsuke, Furukawa, Nayuta, Arai, Kazuhito, Nakajima, Masahiro, Taguchi, Hayao

Journal:

Biochemical and Biophysical Research Communications

Année:

2013

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2013

12

Biosynthesis of natural products containing β-amino acids

Kudo, Fumitaka, Miyanaga, Akimasa, Eguchi, Tadashi

Journal:

Natural Product Reports

Année:

2014

Langue:

english

Fichier:

PDF, 2.18 MB

english, 2014

13

Discovery and Assembly-Line Biosynthesis of the Lymphostin Pyrroloquinoline Alkaloid Family of mTOR Inhibitors in Salinispora Bacteria

Miyanaga, Akimasa, Janso, Jeffrey E., McDonald, Leonard, He, Min, Liu, Hongbo, Barbieri, Laurel, Eustáquio, Alessandra S., Fielding, Elisha N., Carter, Guy T., Jensen, Paul R., Feng, Xidong, Leighton

Journal:

Journal of the American Chemical Society

Année:

2011

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2011

14

Characterization of Polyphosphate Glucokinase SCO5059 from Streptomyces coelicolor A3(2)

KOIDE, Mai, MIYANAGA, Akimasa, KUDO, Fumitaka, EGUCHI, Tadashi

Journal:

Bioscience Biotechnology and Biochemistry

Année:

2013

Langue:

english

Fichier:

PDF, 117 KB

english, 2013

15

Genome Mining of the Hitachimycin Biosynthetic Gene Cluster: Involvement of a Phenylalanine-2,3-aminomutase in Biosynthesis

Kudo, Fumitaka, Kawamura, Koichi, Uchino, Asuka, Miyanaga, Akimasa, Numakura, Mario, Takayanagi, Ryuichi, Eguchi, Tadashi

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 669 KB

english, 2015

16

Diverse allosteric and catalytic functions of tetramericd-lactate dehydrogenases from three Gram-negative bacteria

Furukawa, Nayuta, Miyanaga, Akimasa, Togawa, Misato, Nakajima, Masahiro, Taguchi, Hayao

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 585 KB

english, 2014

17

Crystallization and preliminary X-ray diffraction analysis of Lin1840, a putative β-glucosidase from Listeria innocua

Nakajima, Masahiro, Yoshida, Ryuta, Miyanaga, Akimasa, Taguchi, Hayao

Journal:

Acta Crystallographica Section F Structural Biology Communications

Année:

2014

Langue:

english

Fichier:

PDF, 204 KB

english, 2014

18

Mechanism-based Trapping of the Quinonoid Intermediate Using the K276R Mutant of PLP-Dependent 3-Aminobenzoate Synthase PctV in the Biosynthesis of Pactamycin

Hirayama, Akane, Miyanaga, Akimasa, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 983 KB

english, 2015

19

Identification of the Fluvirucin B 2 (Sch 38518) Biosynthetic Gene Cluster from Actinomadura fulva subsp. indica ATCC 53714: substrate Specificity of the β-Amino Acid Selective Adenylating Enzyme FlvN

Miyanaga, Akimasa, Hayakawa, Yuki, Numakura, Mario, Hashimoto, Junko, Teruya, Kuniko, Hirano, Takashi, Shin-ya, Kazuo, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Bioscience Biotechnology and Biochemistry

Année:

2016

Langue:

english

Fichier:

PDF, 500 KB

english, 2016

20

Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis

Miyanaga, Akimasa, Iwasawa, Shohei, Shinohara, Yuji, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Proceedings of the National Academy of Sciences

Année:

2016

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2016

21

Parallel Post-Polyketide Synthase Modification Mechanism Involved in FD-891 Biosynthesis in Streptomyces graminofaciens A-8890

Kudo, Fumitaka, Kawamura, Koichi, Furuya, Takashi, Yamanishi, Hiroto, Motegi, Atsushi, Komatsubara, Akiko, Numakura, Mario, Miyanaga, Akimasa, Eguchi, Tadashi

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 605 KB

english, 2016

22

The family 42 carbohydrate-binding module of family 54 α-L-arabinofuranosidase specifically binds the arabinofuranose side chain of hemicellulose

Miyanaga, Akimasa, Koseki, Takuya, Miwa, Yozo, Mese, Yuichiro, Nakamura, Sachiko, Kuno, Atsushi, Hirabayashi, Jun, Matsuzawa, Hiroshi, Wakagi, Takayoshi, Shoun, Hirofumi, Fushinobu, Shinya

Journal:

Biochemical Journal

Année:

2006

Langue:

english

Fichier:

PDF, 533 KB

english, 2006

23

Mechanisms of β-amino acid incorporation in polyketide macrolactam biosynthesis

Miyanaga, Akimasa, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Current Opinion in Chemical Biology

Année:

2016

Langue:

english

Fichier:

PDF, 801 KB

english, 2016

24

Biochemical and Structural Analyses of a Bacterial Endo-β-1,2-Glucanase Reveal A New Glycoside Hydrolase Family

Abe, Koichi, Nakajima, Masahiro, Yamashita, Tetsuro, Matsunaga, Hiroki, Kamisuki, Shinji, Nihira, Takanori, Takahashi, Yuta, Sugimoto, Naohisa, Miyanaga, Akimasa, Nakai, Hiroyuki, Arakawa, Takatoshi,

Journal:

Journal of Biological Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 9.33 MB

english, 2017

25

Biochemical characterization and structural insight into aliphatic β-amino acid adenylation enzymes IdnL1 and CmiS6

Cieślak, Jolanta, Miyanaga, Akimasa, Takaku, Ryoma, Takaishi, Makoto, Amagai, Keita, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2017

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2017

26

The ternary complex structure of d -mandelate dehydrogenase with NADH and anilino(oxo)acetate

Furukawa, Nayuta, Miyanaga, Akimasa, Nakajima, Masahiro, Taguchi, Hayao

Journal:

Biochemical and Biophysical Research Communications

Année:

2017

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2017

27

Mechanistic insight into the substrate specificity of 1,2-β-oligoglucan phosphorylase from Lachnoclostridium phytofermentans

Nakajima, Masahiro, Tanaka, Nobukiyo, Furukawa, Nayuta, Nihira, Takanori, Kodutsumi, Yuki, Takahashi, Yuta, Sugimoto, Naohisa, Miyanaga, Akimasa, Fushinobu, Shinya, Taguchi, Hayao, Nakai, Hiroyuki

Journal:

Scientific Reports

Année:

2017

Langue:

english

Fichier:

PDF, 2.02 MB

english, 2017

28

Structural analysis of the dual function thioesterase SAV606 unravels the mechanism of Michael addition of glycine to an α,β-unsaturated thioester

Chisuga, Taichi, Miyanaga, Akimasa, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Journal of Biological Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 2.71 MB

english, 2017

29

Substrate recognition by a dual functional P450 monooxygenase GfsF involved in FD-891 biosynthesis

Eguchi, Tadashi, Miyanaga, Akimasa, Takayanagi, Ryuichi, Furuya, Takashi, Kawamata, Ayano, Itagaki, Tomohiro, Iwabuchi, Yoshiharu, Kanoh, Naoki, Kudo, Fumitaka

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 3.41 MB

english, 2017

30

Structure and function of polyketide biosynthetic enzymes: various strategies for production of structurally diverse polyketides

Miyanaga, Akimasa

Journal:

Bioscience Biotechnology and Biochemistry

Année:

2017

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2017

31

Function and structure relationships of a β-1,2-glucooligosaccharide-degrading β-glucosidase

Ishiguro, Rikuto, Tanaka, Nobukiyo, Abe, Koichi, Nakajima, Masahiro, Maeda, Takuma, Miyanaga, Akimasa, Takahashi, Yuta, Sugimoto, Naohisa, Nakai, Hiroyuki, Taguchi, Hayao

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.31 MB

english, 2017

32

10.1271/kagakutoseibutsu.52.830

KUDO, Fumitaka, MIYANAGA, Akimasa, EGUCHI, Tadashi

Année:

2014

Fichier:

PDF, 2.07 MB

2014

33

Characterization and Structural Analysis of a Novel exo -Type Enzyme Acting on β-1,2-Glucooligosaccharides from Parabacteroides distasonis

Shimizu, Hisaka, Nakajima, Masahiro, Miyanaga, Akimasa, Takahashi, Yuta, Tanaka, Nobukiyo, Kobayashi, Kaito, Sugimoto, Naohisa, Nakai, Hiroyuki, Taguchi, Hayao

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 2.45 MB

english, 2018

34

Structural basis of protein–protein interactions between a trans-acting acyltransferase and acyl carrier protein in polyketide disorazole biosynthesis

Miyanaga, Akimasa, Ouchi, Risako, Ishikawa, Fumihiro, Goto, Ena, Tanabe, Genzoh, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Journal of the American Chemical Society

Année:

2018

Langue:

english

Fichier:

PDF, 2.11 MB

english, 2018

35

Functional and Structural Analysis of a β-Glucosidase Involved in β-1,2-Glucan Metabolism in Listeria innocua

Nakajima, Masahiro, Yoshida, Ryuta, Miyanaga, Akimasa, Abe, Koichi, Takahashi, Yuta, Sugimoto, Naohisa, Toyoizumi, Hiroyuki, Nakai, Hiroyuki, Kitaoka, Motomitsu, Taguchi, Hayao, Silman, Israel

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 5.33 MB

english, 2016

36

Biochemical and Structural Analysis of FomD That Catalyzes the Hydrolysis of Cytidylyl ( S )-2-Hydroxypropylphosphonate in Fosfomycin Biosynthesis

Sato, Shusuke, Miyanaga, Akimasa, Kim, Seung-Young, Kuzuyama, Tomohisa, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 2.37 MB

english, 2018

37

Structural basis of sequential allosteric transitions in tetrameric D-lactate dehydrogenases from three Gram-negative bacteria

Furukawa, Nayuta, Miyanaga, Akimasa, Nakajima, Masahiro, Taguchi, Hayao

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 39.24 MB

english, 2018

38

Structural basis of the nonribosomal codes for nonproteinogenic amino acid selective adenylation enzymes in the biosynthesis of natural products

Kudo, Fumitaka, Miyanaga, Akimasa, Eguchi, Tadashi

Journal:

Journal of Industrial Microbiology & Biotechnology

Année:

2018

Langue:

english

Fichier:

PDF, 4.27 MB

english, 2018

39

Michael additions in polyketide biosynthesis

Miyanaga, Akimasa

Journal:

Natural Product Reports

Année:

2019

Langue:

english

Fichier:

PDF, 2.92 MB

english, 2019

40

An engineered aryl acid adenylation domain with a capacious active site microenvironment

Ishikawa, Fumihiro, Miyanaga, Akimasa, Kitayama, Hinano, Nakamura, Shinya, Nakanishi, Isao, Kudo, Fumitaka, Eguchi, Tadashi, Tanabe, Genzoh

Journal:

Angewandte Chemie International Edition

Année:

2019

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2019

41

An engineered aryl acid adenylation domain with a capacious active site microenvironment

Ishikawa, Fumihiro, Miyanaga, Akimasa, Kitayama, Hinano, Nakamura, Shinya, Nakanishi, Isao, Kudo, Fumitaka, Eguchi, Tadashi, Tanabe, Genzoh

Journal:

Angewandte Chemie

Année:

2019

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2019

42

Identification, characterization and structural analyses of a fungal endo -β-1,2-glucanase reveal a new glycoside hydrolase family

Tanaka, Nobukiyo, Nakajima, Masahiro, Narukawa-Nara, Megumi, Matsunaga, Hiroki, Kamisuki, Shinji, Aramasa, Hiroki, Takahashi, Yuta, Sugimoto, Naohisa, Abe, Koichi, Terada, Tohru, Miyanaga, Akimasa, Ya

Journal:

Journal of Biological Chemistry

Année:

2019

Langue:

english

Fichier:

PDF, 2.72 MB

english, 2019

43

Structural Analysis of the Glycine Oxidase Homolog CmiS2 Reveals a Unique Substrate Recognition Mechanism for Formation of a β-Amino Acid Starter Unit in Cremimycin Biosynthesis

Kawasaki, Daisuke, Chisuga, Taichi, Miyanaga, Akimasa, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 448 KB

english, 2019

44

New Structural Insights on Carbohydrate-active Enzymes

Fushinobu, Shinya, Hidaka, Masafumi, Miyanaga, Akimasa, Imamura, Hiromi

Journal:

Journal of Applied Glycoscience

Année:

2007

Fichier:

PDF, 395 KB

2007

45

Functional and Structural Analyses of the Split-Dehydratase Domain in the Biosynthesis of Macrolactam Polyketide Cremimycin

Kawasaki, Daisuke, Miyanaga, Akimasa, Chisuga, Taichi, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 2.32 MB

english, 2019

46

Stereochemistry in the Reaction of the myo -Inositol Phosphate Synthase Ortholog Ari2 during Aristeromycin Biosynthesis

Kudo, Fumitaka, Tsunoda, Takeshi, Yamaguchi, Kaito, Miyanaga, Akimasa, Eguchi, Tadashi

Journal:

Année:

2019

Fichier:

PDF, 2.06 MB

2019

47

Biochemical and Structural Analysis of a Dehydrogenase, KanD2, and an Aminotransferase, KanS2, That Are Responsible for the Construction of the Kanosamine Moiety in Kanamycin Biosynthesis

Kudo, Fumitaka, Kitayama, Yukinobu, Miyanaga, Akimasa, Hirayama, Akane, Eguchi, Tadashi

Journal:

Année:

2020

Fichier:

PDF, 1.38 MB

2020

48

Generation of incednine derivatives by mutasynthesis

Miyanaga, Akimasa, Takaku, Ryoma, Takaishi, Makoto, Tashiro, Etsu, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

The Journal of Antibiotics

Année:

2020

Fichier:

PDF, 638 KB

2020

49

Structural characterization of complex of adenylation domain and carrier protein by using pantetheine cross-linking probe

Miyanaga, Akimasa, Kurihara, Shohei, Chisuga, Taichi, Kudo, Fumitaka, Eguchi, Tadashi

Journal:

ACS Chemical Biology

Année:

2020

Fichier:

PDF, 1.56 MB

2020